Human Hydatid Disease in Peru Is Basically Restricted to Echinococcus granulosus Genotype G1

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Date
2010-10-01Author
Santiváñez, Saúl J.
Gutiérrez, Mariana M.
Rosenzvit, Mara C.
Muzulin, Patricia M.
Rodríguez, Mary L.
González, Armando E.
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A molecular PCR study using DNA from 21 hydatid cysts was performed to determine which strain type
is responsible for human infection in Peru. The mitochondrial cytochrome c oxidase subunit 1 (CO1) gene was amplified
in 20 out of 21 samples, revealing that all but 1 sample (19/20, 95%) belonged to the common sheep strain (G1). The
remaining samples belonged to the camel strain (G6). The G1 genotype was most frequently found in human cases of
cystic hydatid disease (CHD) in Peru. Local control measures should focus primarily on decreasing dog and sheep
infection rather than intermediate reservoirs.
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